Toxicological evaluation at IIBR is followed by the generation of novel treatment protocols and drugs, rapid and effective solutions for damage prevention and control. These are gained by a combination of cutting-edge synthetic capabilities and an advanced analytical toolbox. All are based on comprehensive pharmacological and pathophysiological understanding and advanced experimental means.
From the design table to fully characterized compounds. Expertise in designing and conducting synthetic routes, including working in dry conditions, multi-component syntheses, various polymerizations, nanoparticles manufacturing, etc. In-house characterization of the desired products.
IIBR has a team of professionals at the forefront of their disciplines, highly experienced in the analysis of environmental, pharmaceutical and biological samples. R&D at the center is conducted using state-of-the-art technologies and assisted by active collaborations with leaders in the fields of organic and medicinal chemistry, pharmacology, biology and environmental sciences. We provide high quality complete analytical solutions for detection, identification and quantitation of target compounds, as well as screening for "unknowns", including "OMICS" approaches. Analytes vary in their physical and chemical properties, from gases to non-volatiles and thermolabiles, polar to non-polar organic compounds, extracted from various matrices. We develop complete analytical processes, from sampling methods through sample preparation for instrumental analysis to data processing protocols. Each method is carefully validated.The analytical center includes two major instrumental sections: GC/MS and LC/MS
The behavioral monitoring unit at the Department of Pharmacology specializes in behavioral assessment of manipulations of interest (pharmacological and others) in both animal models and humans
Our team of researchers focuses on understanding the toxicological process following exposure to a variety of toxicants and on developing and evaluating therapeutic measures for their prevention.
Design of biologically active molecules, based on computerized modeling and subsequent prioritization. Testing and pharmacological evaluation of these molecules, both in vitro and in vivo, using a vast variety of animal models.
Commited to the importance of clean environment, we put much effort in develop better ways to detect toxic pollutants, research their degradation pathways and complete the task with novel tools for their elimination
We welcome you to contact us for any question or offer for collaborations.
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